Joseph Timms was a former SHIELD lab worker stationed in the Florida Everglades during the events of the S.H.I.E.L.D. Civil War. When that occurred, the HYDRA agents in the facility attacked him, intending to keep him silent about their operations. Timms managed to fight them off for as long as he could, but as he retreated into a nearby swamp for safety, he was shot in the back and died immediately afterwards, his body floating belly up in the swamp water.
His corpse was eventually recovered by several HYDRA agents and brought to Professor Samuel Sterns' headquarters for genetic experimentation, where it was submerged repeatedly in a tank of gamma irradiated serum mixed with swamp plants. The gamma serum mutated and resurrected Timms' body into a mindless golem-like creature known as the Glob, who soon fell under the Leader's mental control to serve his interests in building a "Gamma Force".